Stanford

Clarke Laboratories

home // FACULTY AND STAFF // Clarke Laboratories

  • ABOUT
  • NEWS RELEASE
  • RECENT PUBLICATIONS
  • VIDEO
  • CONTACT INFO

Michael
Clarke

MD,PhD

Michael Clarke

The Clarke lab works on the molecular regulation of self-renewal in normal stem cells and cancer. Modulation of these self renewal pathways are being explored as potential therapeutic targets for regenerative medicine and cancer.

Back to Top

Recent Publications

Removal of lactate dehydrogenase-elevating virus from human-in-mouse breast tumor xenografts by cell-sorting. Liu H, Bockhorn J, Dalton R, Chang YF, Qian D, Zitzow LA, Clarke MF, Greene GL. J Virol Methods. 2011; 173 (2): 266-70

Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models. Liu H, Patel MR, Prescher JA, Patsialou A, Qian D, Lin J, Wen S, Chang YF, Bachmann MH, Shimono Y, Dalerba P, Adorno M, Lobo N, Bueno J, Dirbas FM, Goswami S, Somlo G, Condeelis J, Contag CH, Gambhir SS, Clarke MF. Proc Natl Acad Sci U S A. 2010; 107 (42): 18115-20

Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Shimono Y, Zabala M, Cho RW, Lobo N, Dalerba P, Qian D, Diehn M, Liu H, Panula SP, Chiao E, Dirbas FM, Somlo G, Pera RA, Lao K, Clarke MF. Cell. 2009; 138 (3): 592-603

Association of reactive oxygen species levels and radioresistance in cancer stem cells. Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, Qian D, Lam JS, Ailles LE, Wong M, Joshua B, Kaplan MJ, Wapnir I, Dirbas FM, Somlo G, Garberoglio C, Paz B, Shen J, Lau SK, Quake SR, Brown JM, Weissman IL, Clarke MF. Nature. 2009; 458 (7239): 780-3

Back to Top

Video

Back to Top

Contact Info

1050 Arastradero Road (Lower Bldg)
Room A151, MC: 5542
Palo Alto, California 94304

Phone: (650) 498-5852
Phone: (650) 725-2495

mfclarke@stanford.edu

Back to Top