Wu Laboratory

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Joseph Wu

The Wu lab studies the biological mechanisms of adult stem cells, embryonic stem cells, and induced pluripotent stem cells. We use a combination of next generation sequencing, tissue engineering, physiological testing, and molecular imaging technologies to better understand stem cell biology in vitro and in vivo. For adult stem cells, we are interested in monitoring stem cell survival, proliferation, and differentiation. For embryonic stem cells, we are currently studying their tumorigenicity, immunogenicity, and differentiation. For induced pluripotent stem cells, we are interested in cadiovascular disease modeling, drug screening, and cell therapy. We also develop novel vectors and therapeutic genes for cardiovascular gene therapy applications.

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Recent Publications

Patient-specific stem cells and cardiovascular drug discovery. JAMA-the journal of the American Medical Association
Mordwinkin, N. M., Lee, A. S., Wu, J. C.
2013; 310 (19): 2039-2040

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies. Nature medicine
Lee, A. S., Tang, C., Rao, M. S., Weissman, I. L., Wu, J. C.
2013; 19 (8): 998-1004

Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells CELL STEM CELL
Lan, F., Lee, A. S., Liang, P., Sanchez-Freire, V., Nguyen, P. K., Wang, L., Han, L., Yen, M., Wang, Y., Sun, N., Abilez, O. J., Hu, S., Ebert, A. D., Navarrete, E. G., Simmons, C. S., Wheeler, M., Pruitt, B., Lewis, R., Yamaguchi, Y., Ashley, E. A., Bers, D. M., Robbins, R. C., Longaker, M. T., Wu, J. C.
2013; 12 (1): 101-113

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Contact Info

265 Campus Drive G1120B
Stanford, CA 94305-5463

Phone: (650) 725-7964

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